This review comprehensively summarizes the advantages that nanotechnology holds for vaccine development, as well as the current situation of nanotechnology-enabled vaccine development against the COVID-19 pandemic, with a focus on the interplay between nanotechnology and the host immune system.
Abstract:
Coronavirus disease 2019 (COVID-19) continually poses a significant threat to the human race, and prophylactic vaccination is the most potent approach to end this pandemic. Nanotechnology is widely adopted during COVID-19 vaccine development, and the engineering of nanostructured materials such as nanoparticles has opened new possibilities in innovative vaccine development by improving the design and accelerating the development process. This review aims to comprehensively understand the current situation and prospects of nanotechnology-enabled vaccine development against the COVID-19 pandemic, with an emphasis on the interplay between nanotechnology and the host immune system.
Author list:
Wang Ziqi†, Cui Kai†, Ulrich Costabel*, Zhang Xiaoju*
How to cite:
W. Ziqi, C. Kai, U. Costabel, Z. Xiaoju, Exploration 2022, 2, 20210082.
https://doi.org/10.1002/EXP.20210082