Recent advancements in implantable neural links based on organic synaptic transistors

Rapid advancement in brain synaptic devices uses field effect transistors to simulate human brain synapses. Organic semiconductors, which are noted for their simplicity and biocompatibility, have enormous potential in brain synaptic bioelectronics. This review discusses ongoing obstacles, even with employment in integrated circuits and brain networks, and covers recent improvements, their application, and future research prospects.


The progress of brain synaptic devices has witnessed an era of rapid and explosive growth. Because of their integrated storage, excellent plasticity and parallel computing, and system information processing abilities, various field effect transistors have been used to replicate the synapses of a human brain. Organic semiconductors are characterized by simplicity of processing, mechanical flexibility, low cost, biocompatibility, and flexibility, making them the most promising materials for implanted brain synaptic bioelectronics. Despite being used in numerous intelligent integrated circuits and implantable neural linkages with multiple terminals, organic synaptic transistors still face many obstacles that must be overcome to advance their development. A comprehensive review would be an excellent tool in this respect. Therefore, the latest advancements in implantable neural links based on organic synaptic transistors are outlined. First, the distinction between conventional and synaptic transistors are highlighted. Next, the existing implanted organic synaptic transistors and their applicability to the brain as a neural link are summarized. Finally, the potential research directions are discussed.

Author list:

Swarup Biswas, Hyo-won Jang, Yongju Lee, Hyojeong Choi, Yoon Kim*, Hyeok Kim*, Yangzhi Zhu*

How to cite:

S. Biswas, H.-w. Jang, Y. Lee, H. Choi, Y. Kim, H. Kim, Y. Zhu, Exploration 2023, 4, 20220150.