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Mitochondria-targeted nanoparticles in treatment of neurodegenerative diseases

This review summarized the advantages and challenges of nanotechnology-based mitochondrial-targeted therapy for neurodegenerative diseases (NDs). In this review, relationships between mitochondrial dysfunction and NDs are discussed; the applications of various NPs in treatment and diagnosis of mitochondrial dysfunction related NDs are also introduced. Abstract: Neurodegenerative diseases (NDs) are a class of heterogeneous diseases that includes …

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Ultrasound-controlled drug release and drug activation for cancer therapy

This review presents a comprehensive summary of the current understanding of ultrasound-sensitive drug delivery systems for controlled drug release and drug activation. The typical mechanisms and the main factors affecting the ultrasonic responsiveness of drug carriers are summarized. Representative examples of ultrasound-controlled drug release and drug activation are highlighted. Abstract: Traditional chemotherapy suffers from severe …

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Exploring new battery knowledge by advanced characterizing technologies

Advanced characterizing technologies are of critical importance in enabling the revealing of materials regarding their structural and chemical information, eventually establishing the correlations between microstructures and properties at the multiscale levels. Abstract: Exploration of science and technologies represents human’s thirst for new knowledge and new life. Presently, we are in a stage of transferring the …

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Schiff-bases for sustainable battery and supercapacitor electrodes

A Schiff-base reaction is a condensation reaction between amine and carbonyl groups. It can be used to synthesize various organic materials. The precursors are often low-cost, and the synthesis utilizes mild conditions without the use of toxic chemicals. Therefore, these materials gained significant attention for sustainable electrodes. In this review, we discuss their applicability for …

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Advanced bioactive nanomaterials for biomedical applications

In this review, we summary the recent advances of bioactive nanomaterials, and discuss the influence factors of bioactivities including the physical structure of bioactive nanomaterials, surface properties, and nanotopography. Then, a range of bioactive nanomaterials, including inorganic nanomaterials, carbon-based nanomaterials, polymeric nanomaterials, and supramolecular-based nanomaterials are discussed. In addition, we also introduce several typical applications …

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3D-printed microneedles with open groove channels for liquid extraction

This report describes the 3D fabrication of the microneedles with the open groove channels for skin interstitial fluid extraction through capillary force. Biomarkers in the extracted liquid (e.g. glucose) can be analyzed in situ by the commercial test strips attached to the back of microneedles. Abstract: Microneedles (MNs) offer a simple and minimally invasive way …

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Advanced microfluidic devices for fabricating multi‐structural hydrogel microsphere

The review summarizes the features of hydrogel microspheres and microfluidic technique, followed by the discussion of material selection in fabricating microfluidic device. Then the progress of microfluidic devices for both single-component and composite hydrogel microspheres is described. Finally, this review discusses the key research direction and application of microfluidics for hydrogel microsphere in the future. …

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Advances in 4D‐printed physiological monitoring sensors

This perspective focuses on the overview of 4D printing, its history, and both wearable and implantable physiological sensing solutions. The current challenges faced in this field, translational research, and its future prospects are explored. All of these aims highlight key areas of attention that can be applied by future researchers to fully transform 4D printed …

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Hydrogen production coupled with water and organic oxidation based on layered double hydroxides

In this review, we have summarized the latest research progress of hydrogen production from the perspectives of designing efficient LDHs-based electrocatalysts for OER and EHCO. Meanwhile, the challenges in the field of hydrogen production via electrochemical water splitting coupled with organic oxidation have been raised. Abstract: Hydrogen production via electrochemical water splitting is one of …

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Multisite PCET with photocharged carbon nitride in dark

Nature relies on the exploitation of sunlight and hydrogen ions to enable uphill organic reactions, namely photosynthesis. Herein, a biomimetic organic semiconductor composed of abundant elements (C, N, and K) uses this strategy to accumulate light energy and store hydrogen ions as powerful tool for synthetic organic chemistry in the flask. Abstract: A combination of …

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