Burst of hopping trafficking correlated reversible dynamic interactions between lipid droplets and mitochondria under starvation
The reversible interactions between LDs and mitochondria are tracked in real-time using a robust LDs-specific fluorescent probe (LDs-Tags). LDs exhibit active transport and are inclined to repeatedly search for a suitable contact site on the mitochondrial membrane under nutrient starvation. Intermittent larger jumps are observed between clustered small steps during this process. Abstract: Dynamic membrane …