Great progress has been made in ingenious bone tissue engineering for osteonecrosis of the femoral head (ONFH) treatment in the last decades. In this review, we comprehensively summarize the state-of-the-art progress made in bone tissue engineering for ONFH treatment. We also propose insights on the current challenges of these advances in the clinic and the …
Mobile mechanical signal generator for macrophage polarization Read More »
In this review, we have summarized the development of different types of COFs-based composites reported so far, with particular focus on the representative applications of COFs-based composites, and the in-depth insight into their current challenges and future development prospects. We anticipate that this review may provide some inspiration and insights for the further development of …
We demonstrate a robust memcapacitor by stacking ferroelectric capacitor on the metal-insulator-semiconductor structure. It possesses a long retention time of more than 104 s and well endurance of 109 cycles. Ultralow-power in-memory computing based on ferroelectric memcapacitor array intrinsically consumes zero energy in memcapacitors themselves. It sheds light on an ultralow-power neural hardware based on ferroelectric memcapacitors. …
Ultralow-power in-memory computing based on ferroelectric memcapacitor network Read More »
Aptamer-functionalized field-effect transistor (FET) biosensors with merits of fast response speed, ease of miniaturization, and integration offer an attractive solution to disease diagnosis and environmental monitoring. This review is focusing on the development of aptamer-functionalized FET biosensors from sensing mechanism to functionalization strategy to biological application level, combined with the latest research and in-depth outlook, …
Owing to the synergy between highly dispersed active sites and particular substrates with the one-dimensional nanostructure, fibrous carbon-based nanoreactors have exhibited fascinating electrocatalytic performance in electrochemical reactions. Therefore, one-dimensional fibrous carbon-based nanoreactors from the electrospun fabrication process have been used in catalyzing oxygen reduction reaction, oxygen evolution reaction, and hydrogen evolution reaction electrochemical reactions. Abstract: …
Hippocampal Cntnap4 deficiency was associated with cognitive impairment via inducing pro-inflammatory response in females. A biomimetic microglial nanoparticle system (MNPs@PLX) was established for precise microglial delivery of FDA-approved PLX3397 to attenuate cognitive decline, dysfunctional synaptic plasticity, and pro-inflammatory response in female heterozygous Cntnap4 knockout mice. This study indicates that microglial supplementation of PLX3397 may serve as an intervention for …
Microglial targeted therapy relieves cognitive impairment caused by Cntnap4 deficiency Read More »
Silica based nanoparticles have been extensively applied in nanomedicine including cancer immunotherapy. In this review, the applications of mesoporous silica nanoparticles (MSN), mesoporous organosilica nanoparticles (MON), and metal-doped MSN/MON in the field of cancer immunotherapy and tumor microenvironment regulation are comprehensively summarized by highlighting the structural and compositional attributes of the silica-based nanoplatforms. Abstract: Cancer …
Mesoporous silica/organosilica nanoparticles for cancer immunotherapy Read More »
Harnessing the immune system to attack the tumor with cancer vaccines is being intensively studied. Nowadays, biomimetic and bioinspired nanotechnology provides new impetus for the designing concepts of cancer vaccines. The specific behaviors and endogenous molecules of each type of living entity (eukaryotic cell or microorganism) offer unique features to address specific needs for cancer …
Biomimetic and bioinspired nano-platforms for cancer vaccine development Read More »
Many organisms had formed ingenious optical structures for the efficient emission of light signals in the environment during the long-term evolution. We summarized detailed examples of bio-inspired optical structures in enhanced luminescence and presented the applications of these inspirations in information encryption, biochemical detection, and luminescent sources. Our work will provide profound guidance for bio-inspired …
Bio-inspired optical structures for enhancing luminescence Read More »
Compared to NPs, Ligand-protected NCs with atomically precise structures and monodispersity have become an ideal candidate for understanding the well-defined correlations between structure and catalytic property at an atomic level. Tuning the kernel structure of NCs to improve catalytic activity and selectivity by tailoring the number, types, and positions of metal atoms is a novel …
