the Author

Tracking tumor heterogeneity and progression with near-infrared II fluorophores

The applications of NIR-II Fluorophores in tracking the heterogeneity and progression of tumors. The advances in imaging the tumor heterogeneity, progression, and therapy are systematically summarized. As a non-invasive visualized inspection modality, NIR-II imaging further enables a deeper understanding of tumor pathophysiology and is envisioned for potential clinical translation. Abstract: Heterogeneous cells are the main …

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Bone tissue engineering for treating osteonecrosis of the femoral head

Great progress has been made in ingenious bone tissue engineering for osteonecrosis of the femoral head (ONFH) treatment in the last decades. In this review, we comprehensively summarize the state-of-the-art progress made in bone tissue engineering for ONFH treatment. We also propose insights on the current challenges of these advances in the clinic and the …

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Opportunities and challenges of hole transport materials for high-performance inverted hybrid-perovskite solar cells

In this perspective, the recent advancements of inverted perovskite solar cells based on diverse hole transport materials, including polymer-, copper-, nickel-based and self-assembled monolayers and others, have been systematically reviewed. In addition, the current research issues and possible future directions for industry applications are given from the authors’ point of view. Abstract: Inverted perovskite solar …

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Recent advances of Au@Ag core–shell SERS-based biosensors

Bimetallic alloy Au–Ag surface-enhanced Raman scattering (SERS) biosensors exhibit ultrahigh SERS sensitivity. Au–Ag SERS-based biosensors have been utilized in biological components detection, including; proteins, antigens antibodies complex, circulating tumor cells, DNA, and RNA (miRNA), etc. Abstract: The methodological advancements in surface-enhanced Raman scattering (SERS) technique with nanoscale materials based on noble metals, Au, Ag, and …

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Recent advances in targeted antibacterial therapy basing on nanomaterials

To address the challenge of antibiotic-resistant bacteria, nanomaterials-mediated targeted bacteria depletion in either a passive or active manner has emerged as one of the most promising approaches for antibacterial treatment. In this review, we summarize the recent development in the field of targeted antibacterial therapy based on nanomaterials, which show advantages in increasing local concentration …

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Revolving ATPase motors as asymmetrical hexamers in translocating lengthy dsDNA via conformational changes and electrostatic interactions in phi29, T7, herpesvirus, mimivirus, E. coli, and Streptomyces

The revolving DNA motors of ATPase have been found in viruses (phi29, T7, herpesvirus, and mimivirus) and bacteria (E. coli and Streptomyces). The motors made of asymmetrical 6 subunits translocate lengthy double-stranded (ds)DNA. The dsDNA is moved in a circular motion around the inner surface of the motor channel subunits. The translocation involves conformational changes and electrostatic interactions …

Revolving ATPase motors as asymmetrical hexamers in translocating lengthy dsDNA via conformational changes and electrostatic interactions in phi29, T7, herpesvirus, mimivirus, E. coli, and Streptomyces Read More »

Recent advances in two-dimensional materials for hydrovoltaic energy technology

Hydrovoltaic energy technology that generates electricity directly from the interaction of materials with water has been regarded as a promising renewable energy harvesting method. This review summarizes the most recent advances of 2D materials for hydrovoltaic electricity generation, including carbon nanosheets, layered double hydroxide, and layered transition metal oxides and sulfides. Perspectives toward the future …

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Microneedle system for tissue engineering and regenerative medicine

In this review, we have summarized the state-of-the-art microneedles for tissue engineering and regenerative medicine, from their classifications and rational design, to the representative applications involving maintenance and rehabilitation of damaged tissues and organs, and the in-depth insight into their current challenges and future directions. Abstract: Global increasing demand for high life quality and length …

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Graphene: Preparation, tailoring, and modification

Graphene is a key material for a new generation of electronic devices with unique electrical properties. In this review, current advances in the preparation, tailoring, and modification of graphene to obtain high-quality graphene with precisely controlled patterning and specific functional groups are summarized. Abstract: Graphene is a 2D material with fruitful electrical properties, which can …

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Ultrasmall iron-gallic acid coordination polymer nanodots with antioxidative neuroprotection for PET/MR imaging-guided ischemia stroke therapy

Oxidative stress from reactive oxygen species (ROS) is a reperfusion injury factor that can lead to cell damage and death. Ultrasmall Fe-GA CPNs were synthesized to exert a protective role in ischemic brain neurons via removal of ROS, rescuing of glucose metabolism, and suppressing apoptosis through the upregulation of protein kinase B (Akt), antioxidant nuclear …

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