Article

Metal-Organic Frameworks-Based Copper Catalysts for CO2 Electroreduction Toward Multicarbon Products

Article, Review Article / By

This review discusses design principles, preparation approaches, and performance achievements of metal-organic frameworks (MOF)-based Cu catalysts for electrochemical CO2 reduction to C2+ products. The correlation between synthesis, composition/structure, and catalytic properties was critically discussed to reveal catalytic mechanisms and performance-determining factors. The strategies are suggested to address the remaining challenges for designing advanced MOF-based Cu …

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Cancer Immunotherapy Based on the Bidirectional Reprogramming of the Tumor Microenvironment by a “Brakes Off/ Step on the Accelerator” Core-Shell Manganese Phosphate/siPD-L1 Modulator

Article, Research Article / By

To enhance the comprehensive treatment effect of triple-negative breast cancer, a pH-responsive core-shell manganese phosphate nano-regulator was prepared to reprogram the tumor microenvironment bi-directionally. (1) “Brakes off”: Using siPD-L1 to inhibit PD-L1 expression to restore CD8+ T cell function. 2) “Step on the accelerator”: Based on Mn2+’s effect, promoting CD8+ T cell infiltration and maturation. …

Cancer Immunotherapy Based on the Bidirectional Reprogramming of the Tumor Microenvironment by a “Brakes Off/ Step on the Accelerator” Core-Shell Manganese Phosphate/siPD-L1 Modulator Read More »

Dual-Responsive Multi-Functional Silica Nanoparticles With Repaired Mitochondrial Functions for Efficient Alleviation of Spinal Cord Injury

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Targeting mitochondrial dysfunction presents a potential therapeutic approach for treating spinal cord injury. We have successfully designed and synthesized a functional Se@NADH nanodrug system. This system offers neuroprotective and neuroregenerative benefits by modulating mitochondrial function and neutralizing reactive oxygen species, thereby reducing oxidative damage and neuronal apoptosis. Abstract: Preserved/rescued mitochondrial functions have a significant effect …

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Tumor Diagnosis and Treatment Based on Stimuli-Responsive Aggregation of Gold Nanoparticles

Article, Review Article / By

This review summarizes the current strategies for inducing gold nanoparticles aggregation and its advances in tumor diagnosis and treatment. The authors hope this review can provide a valuable reference for the further development of AuNPs clinical applications. Abstract: Gold nanomaterials have been used in the diagnosis and treatment of different tumors due to their unique …

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Recent Progress in Photocathode Interface Engineering for Photoelectrochemical CO2 Reduction Reaction to C1 or C2+ Products

Article, Review Article / By

Strategic interface engineering optimizes photocathode design for enhanced photoelectrochemical CO2 reduction, incorporating cocatalyst engineering, junction engineering, nanostructure engineering, and defect engineering enhances performance efficiency. Abstract: Photoelectrochemical (PEC) systems harness light absorption to initiate chemical reactions, while electrochemical reactions facilitate the conversion of reactants into desired products, ensuring more efficient and sustainable energy conversion in PECs. …

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Hydrovoltaic Power Generation Depend on Wettability at the Liquid–Solid Interface: Mechanisms, Materials, and Applications With Various Resource

Article, Review Article / By

This study explores hydrovoltaic power generation, a promising energy harvesting technology that utilizes water as a renewable energy source to address climate change. Focusing on the interfacial characteristics between solid surfaces and water, the research highlights the underlying mechanisms, material designs, and potential applications of this technology. The findings aim to advance sustainable energy solutions …

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Efficient Ternary Organic Photovoltaic Films for Fast Exciton Separation to Generate Free Radicals for Wastewater Treatment

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For the first time, application results are reported at the intersection of organic photovoltaics and photocatalysis: An insertion strategy based on morphology modulation is proposed to reduce the π–π stacking distance, improve charge transport, and increase device efficiency. Ternary organic photovoltaic films were applied to wastewater treatment, and the removal rate of ionic Sb(III) and …

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Elastic Nanoparticle-Reinforced, Conductive Structural Color Hydrogel With Super Stretchability, Self-Adhesion, Self-Healing as Electrical/Optical Dual-Responsive Visual Electronic Skins

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A conductive structural color hydrogel with highly charged elastic nanoparticles was developed by implementing a simple one-step assembly and photopolymerization strategy that can achieve excellent mechanical robustness, self-adhesiveness, self-healing properties, as well as synchronous electronic and visual signal monitoring for interactively visual electronic skins. Abstract: Developing smart hydrogel with excellent physicochemical properties and multiple signal …

Elastic Nanoparticle-Reinforced, Conductive Structural Color Hydrogel With Super Stretchability, Self-Adhesion, Self-Healing as Electrical/Optical Dual-Responsive Visual Electronic Skins Read More »

Riding a Vascular Time Train to Spatiotemporally Attenuate Thrombosis and Restenosis by Double Presentation of Therapeutic Gas and Biomacromolecules

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This project develops a biomimetic stent coating with a double presentation of therapeutic biomacromolecule VEGF and therapeutic gas NO, which spatiotemporally promotes vessel repair including promoting rapid re-endothelialization, effectively preventing thrombosis, suppressing inflammation and restenosis. Abstract: Endothelial injury is a common occurrence following stent implantation, often leading to complications such as restenosis and thrombosis. To …

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Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

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Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma-associated oncogene-1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional activity and regulates the antiapoptotic mediator’s (Bcl2) expression, which induces …

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