Article

Spatial transcriptomic analysis of the mouse brain following chronic social defeat stress

In this study, Wang et al. explored the potential pathogenesis of chronic social defeat stress (CSDS)-induced depressive-like behaviour in mice using 10× Visium spatial transcriptomics (ST) technique. Many of the depression-related gene changes were identified and more pronounced in the hippocampus (HIP), cortex (Isocortex), and amygdala (AMY) in susceptible (SUS) mice compared to control and resilient …

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The flow of anisotropic nanoparticles in solution and in blood

There is an increased interest in the use of non-spherical nanoparticles for drug delivery as they often display better blood circulation time. However, there is little understanding of the behaviour of these nanoparticles in blood flow. Microfluidic devices can now gain better insight as alignment of anisotropic nanoparticles as well as their margination towards the …

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Manipulating calcium homeostasis with nanoplatforms for enhanced cancer therapy

This review paper provides a comprehensive overview of nanoplatforms that manipulate calcium ions (Ca2+) homeostasis to enhance cancer therapy. It offers a detailed exploration of two Ca2+ regulation strategies employed by these nanoplatforms, including Ca2+ overload and inhibition, and discusses the applications of Ca2+-related nanomaterials in various cell types, such as cancer cells and immune cells. The …

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Early monitoring-to-warning Internet of Things system for emerging infectious diseases via networking of light-triggered point-of-care testing devices

There is still no epidemic surveillance system, implementing prevention and control measures is slow and inefficient. This study developed a rapid point-of-care (POC) testing device for detecting pathogens. Through multi-device networking, an early monitoring and warning system for major infectious diseases was developed. This study makes a contribution to the urgent need for a system …

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Surface engineering Salmonella with pH-responsive polyserotonin and self-activated DNAzyme for better microbial therapy of tumor

This study presents a novel surface modification approach aimed at enhancing the biomedical applications of Salmonella. By employing a facile surface engineering technique involving pH-responsive polyserotonin (PST) and self-activated DNAzyme, the immune clearance and non-specific colonization of Salmonella can be effectively mitigated. The PST coating exhibits the ability to disassemble in acidic tumor microenvironments, thereby facilitating the controlled …

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Progress on quantum dot photocatalysts for biomass valorization

Quantum dots (QDs) catalyzed biomass valorization into high-value-added chemicals and fuels under solar light is an essential measure to achieve the target of carbon neutrality. This review summarizes the current development of the rational design of QDs photocatalysts for efficient biomass valorization including tuning particle size, structure, surface properties, and ligands. Abstract: Biomass with abundant …

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Toward maximum energy density enabled by anode-free lithium metal batteries: Recent progress and perspective

To comprehend the anode-free lithium metal batteries, it is gone into detail in this review about current collector modification, electrolyte optimization, cathode engineering, and regulation of cycling parameters. Abstract: Owing to the emergenceof energy storage and electric vehicles, the desire for safe high-energy-density energy storage devices has increased research interest in anode-free lithium metal batteries …

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Electrospun PEO/PEG fibers as potential flexible phase change materials for thermal energy regulation

Thermal regulating fabrics are highly applicable in various industries such as bandages, wearable devices, clothing, or facemasks. In this work, PEO is electrospun with PEG as the PCM and plasticizer component, which show great compatibility and produce uniform fibers. Presence of PEG significantly improve the fiber’s mechanical properties, and supercooling for PEG component effectively reduce …

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Models of light absorption enhancement in perovskite solar cells by plasmonic nanoparticles

The experimental literature on plasmonic perovskite solar cells is analyzed in light of this theoretical description. It is estimated that only a small portion of these reports can be associated with light absorption and point out the importance of reporting the perovskite thickness and nanoparticle concentration in order to assess the presence of plasmonic effects …

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Minimally invasive power sources for implantable electronics

This review paper provides a comprehensive overview of the historical development of implantable medical electronics (IMEs) and three main categories of applicable alternative minimally invasive power sources. A detailed discussion of energy storage and harvesting mechanism, configurational design, output power and in vivo applications is given. An outlook based on the current advancements and limitations …

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