Article

Nanoscale electrodeposition: Dimension control and 3D conformality

This review mainly focuses on the nanoscale electrodeposition with respect to dimension control and three-dimensional (3D) conformality. The overall principles of electrodeposition are presented, and the feasible dimensional/morphological control of various materials and the uniform coatings on various substrates are introduced. Abstract: Electrodeposition with a long history has been considered one of the important synthesis …

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Recombinant lactic acid bacteria as promising vectors for mucosal vaccination

Schematic illustration of the locations of expressed antigen by recombinant lactic acid bacteria (LAB) and vaccine strategies applicated in LAB vaccines for enhancing immune responses. Abstract: Lactic acid bacteria (LAB), a diverse family of gram-positive bacteria, has been proven effective in delivering varieties of therapeutic and prophylactic molecules such as antigens and cytokines. Featuring the …

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MXenes as a versatile platform for reactive surface modification and superior sodium-ion storages

Given the potential of MXenes towards Na-ion storage, the recent advances of Na-ion adsorption, intercalation, and migration on MXenes and their hybrids generated from reactive surface modification are summarized. Abstract: Owing to the large surface area and adjustable surface properties, the two-dimensional (2D) MXenes have revealed the great potential in constructing hybrid materials and for …

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Rational ion transport management mediated through membrane structures

Unique membrane structures endow membranes with controlled ion transport properties in both biological and artificial systems, showing broad application prospects in different fields. In this review, current advances in nanochannel-structured membranes for manipulating ion transport are reviewed from the perspective of membrane structures, followed by a discussion of stimulus responsiveness, construction methods, and applications. Finally, …

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Rationally designed modular drug delivery platform based on intracellular peptide self-assembly

A general modulated drug-delivery system based on modulated design has realized effective drug delivery. According to the experimental results and theoretical calculations, the general regulations of molecule design are obtained. The regular prediction and rational molecular design will benefit the further construction and optimization of universal drug delivery platform. Abstract: Modulated molecular design-based intracellular self-assembly …

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The impact of the hypoxia-VEGF-vascular permeability on COVID-19-infected patients

Leaking plasma from blood vessels triggered by COVID-19 infection plays a crucial role in causing pulmonary atelectasis (lung collapse), which fills up the lung air sacs with liquid and the lung becomes deflated. If sufficiently large areas of the lung tissue become deflated by this problem, the lung tissue can no longer take enough air …

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Biomaterials and nanomedicine for bone regeneration: Progress and future prospects

We present an overview of common causes of bone defects, the unmet clinical needs, and the utility of biomaterials and nanotechnology to facilitate bone regeneration. Besides, we propose several key approaches to improve bone repair strategies. This perspective provides a guidance for future research direction of bone repair to improve treatment efficiency in both clinical …

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Super-stable mineralization effect of layered double hydroxides for heavy metals: Application in soil remediation and perspective

Owing to the super-stable mineralization property, layered double hydroxides exhibited excellent performance in soil remediation contaminated by heavy metal ions, providing new strategies and insights into rational designing of amendments in other heavy metals pollution scenarios. Abstract: Agriculture soil plays a crucial role in sustainable development of human society. Unfortunately, soil quality is continuing degradation …

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Dynamically switchable magnetic resonance imaging contrast agents

This perspective highlights the recent development of dynamically switchable MRI contrast agents that can achieve structural transformation and controllable MR signal activation at the disease site in response to various pathological stimuli. Moreover, current challenges and future perspectives of dynamic contrast agents for the accurate detection of microscopic lesions are commented.