Spatial transcriptomic analysis of the mouse brain following chronic social defeat stress
In this study, Wang et al. explored the potential pathogenesis of chronic social defeat stress (CSDS)-induced depressive-like behaviour in mice using 10× Visium spatial transcriptomics (ST) technique. Many of the depression-related gene changes were identified and more pronounced in the hippocampus (HIP), cortex (Isocortex), and amygdala (AMY) in susceptible (SUS) mice compared to control and resilient …