Article

Room temperature liquid metals for flexible alkali metal-chalcogen batteries

Liquid metal (LM) offers a fascinating paradigm for constructing flexible chalcogen batteries. This perspective elaborated the appealing features of LMs and discussed recent advances on LM based battery. The viable strategies and future development of LM-based chalcogen batteries are highlighted. Abstract: Flexibility has become a certain trend in the development of secondary batteries to meet …

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SERS characterization of colorectal cancer cell surface markers upon anti-EGFR treatment

Examining the phenotypes of KRAS mutant and wild-type colorectal cancer cells during anti-EGFR treatment may provide significant insights into drug resistance. Herein, we applied surface-enhanced Raman spectroscopy (SERS) assay to detect four cell surface proteins on KRAS mutant and wild-type cells over a 24-day treatment, where SERS assay achieved multiplexed characterization of cell surface markers …

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Stimuli-responsive crosslinked nanomedicine for cancer treatment

We classify the stimuli-responsive crosslinked nanomedicines (SCNs) into three categories based on the crosslinking strategies, including built-in, on-surface, and inter-particle crosslinking nanomedicines. These SCNs can respond to particular tumoral stimuli and go through a series of dynamic changes to circumvent different biological barriers, and subsequently improve anti-cancer efficacy and imaging sensitivity and specificity. Abstract: Nanomedicines …

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Brain co-delivery of first-line chemotherapy drug and epigenetic bromodomain inhibitor for multidimensional enhanced synergistic glioblastoma therapy

We developed temozolomide and epigenetic bromodomain inhibitor co-encapsulated biomimetic nanomedicine (ABNM@TMZ/OTX) achieved multidimensional enhanced glioblastoma synergistic chemoimmunotherapy in both primary and recurrent orthotopic mice models with significant extended survival rate and little side effects. Abstract: Glioblastoma (GBM) is a central nervous system tumor with poor prognosis due to the rapid development of resistance to mono …

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Interfacial wettability and mass transfer characterizations for gas–liquid–solid triple-phase catalysis

The review focuses on the strategies for evaluating the wettability-controlled mass transfer process at triple-phase interfaces. Ten types of characterizations are described based on photocatalytic and electrocatalytic reactions involving water and gas molecules. Finally, the review discusses the tasks of advanced characterizations to help understand the fundamental reaction mechanism for triple-phase catalysis. Abstract: Heterogeneous catalysis …

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Neural tissue engineering: From bioactive scaffolds and in situ monitoring to regeneration

In this paper, we mainly introduce the recent progress on the construction of nerve conduit for the treatment of peripheral nerve injury, including the design of the conduits in combination with biological effectors and cellular components. In addition, we give perspectives on nerve imaging to allow for the in situ monitoring, and the application of …

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Nanomaterials-assisted metabolic analysis toward in vitro diagnostics

Nanomaterials have found extensive applications in the metabolic analysis of diverse bio-specimens, with efficient selectivity and sensitivity. The nanomaterial-based metabolic analysis is always accompanied by accurate quantitation of targeted metabolite biomarkers and high-throughput profiling of untargeted metabolic fingerprints, adding practical value to in vitro diagnostics. Its further developments will have far-reaching implications for the research …

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Electrodeposition: An efficient method to fabricate self-supported electrodes for electrochemical energy conversion systems

The high-performance electrocatalysts have attracted significant attention to develop efficient energy conversion systems for clean production of hydrogen, hydrocarbon compounds, and ammonia. Electrodeposition is a simple method for fabricating the electrocatalysts with facile control of compositional and morphological properties in aqueous solutions under mild conditions. In this review, recent progress in electrodeposited electrocatalysts is summarized. …

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Light responsive nucleic acid for biomedical application

Light-responsive nucleic acids have attracted much attention in the biomedical field due to their properties of remote control and high spatiotemporal resolution. This review summarizes recent research progress in light-responsive nucleic acid systems. The challenges in this field are discussed and future prospects are prospected. This review will provide inspiration for the rational design of …

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Exceptional point protected robust on-chip optical logic gates

Non-Hermitian physical principles are introduced into the design of on-chip photonic devices toward high robustness. As a proof-of-concept, an exclusive-or gate on silicon-on-insulator platform is designed by employing the exceptional point encirclement physics. The device performance is extremely robust to structural parameter disturbances, owing to the protection of the photon phase by the topological structure around …

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