Review Article

Advanced electrocatalysts for fuel cells: Evolution of active sites and synergistic properties of catalysts and carrier materials

This review describes the evolution of active sites and synergistic properties of catalysts and support materials. In terms of precious metal catalysts, the effects of coordination and synergistic effects, phase structure, crystal surface engineering, and lattice strain were introduced. In non-precious metal catalysts, carbon-based and M-N-C electrocatalysts are introduced. Special emphasis is placed on the …

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Harnessing stimuli-responsive biomaterials for advanced biomedical applications

The application of physical stimulation biomaterials based on ultrasound, light, electricity, and magnetism in the field of biomedicine is summarized, as electrical stimulation of nerve regeneration, electrical stimulation of skin regeneration, electrical stimulation of bone regeneration, photothermal/photodynamic, ultrasound stimulated tissue repair, ultrasonic controlled release, targeting/controlled release, magnetic stimulation tissue repair. Abstract: Cell behavior is intricately …

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Exploring precision treatments in immune-mediated inflammatory diseases: Harnessing the infinite potential of nucleic acid delivery

Within this review, an in-depth exploration of therapeutic nucleic acids and their delivery mechanisms in immune-mediated inflammatory diseases (IMIDs) is presented. The review encapsulates key elements such as different types of nucleic acid molecules, delivery systems for nucleic acids, and the therapeutic use of nucleic acid delivery for IMIDs. Furthermore, the review delves into the …

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Advancements and challenges in brain cancer therapeutics

The review summarizes various treatment options for brain tumors, focusing on their mechanisms, potential side effects, and recent developments. It emphasizes the need for personalized, multi-modal treatment approaches in this rapidly evolving field, balancing efficacy and patient safety. The complexity and diversity of brain tumor treatments are highlighted, advocating for ongoing research and technological advancements …

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Bioactive scaffolds for tissue engineering: A review of decellularized extracellular matrix applications and innovations

We conducted a critical evaluation of decellularization techniques, quality control, cross-linking, and modification methods for dECM scaffolds derived from different sources. The functional properties of dECM components as well as their recent applications in multi-organ tissue engineering and biomedicine were thoroughly reviewed. This work aims to discuss and summarize the current challenges and limitations of …

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Impact of diabetes mellitus on tuberculosis prevention, diagnosis, and treatment from an immunologic perspective

The coexistence of diabetes mellitus (DM) and tuberculosis (TB) presents a significant global burden, with DM being recognized as a major risk factor for TB. This review comprehensively analyzes the immunological aspects of DM-TB comorbidity, shedding light on the impact of DM on TB pathogenesis and immune responses. Moreover, the review explores the effects of …

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Research progress and application of high efficiency organic solar cells based on benzodithiophene donor materials

This summary diagram comprehensively and reasonably reviews the evolution of BDT-based donor materials over the last 20 years by subdividing the molecular design strategies of main-chain engineering, side-chain engineering as well as other engineering based on the detailed molecular structure of BDT-based polymer donors and small molecule donors. Abstract: In recent decades, the demand for …

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Tumor cell membrane-based vaccines: A potential boost for cancer immunotherapy

The review provides a comprehensive overview of the development and application of tumor cell membrane (TCM)-based vaccines for cancer protection and therapy. A detailed description of structure of the TCM-wrapped particles (TCMPs), modification of TCMPs, membrane hybridization, and related adjuvants is given. As a derivative of TCM, the vaccines for tumor-derived-extracellular vesicles (TEVs) are also …

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Long non-coding RNA CASC15 enhances learning and memory in mice by promoting synaptic plasticity in hippocampal neurons

There is an increasing body of evidence suggesting the involvement of long non-coding RNAs (lncRNAs) in neural development and function. Nevertheless, the relationship between lncRNAs and Alzheimer’s disease (AD) remains uncertain. Previous genome-wide association studies (GWAS) have linked cancer susceptibility candidate 15 (CASC15) with AD. This study aims to comprehensively investigate the characteristics and mechanisms …

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Emerging nitric oxide gas-assisted cancer photothermal treatment

A comprehensive review summarizes recent advancements in nitric oxide (NO) gas-assisted cancer photothermal treatment. It commences by providing various types of NO donors/precursors for dual-modal therapy. Subsequently, chemotherapy, photodynamic therapy, alkyl radical therapy, radiation therapy, immunotherapy, chemodynamic therapy, starvation therapy, Ca2+ overload, and ferroptosis are incorporated for triple- and tetra-modal treatment. Abstract: Photothermal therapy (PTT) …

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