A novel nanobody broadly neutralizes SARS-CoV-2 via induction of spike trimer dimers conformation
This study describes a novel nanobody that could induce the trimer dimers conformation of the Spike protein to neutralize the SARS-CoV-2 infection. This nanobody exhibits a broad neutralizing spectrum against various SARS-CoV-2 variants and has the potential to be administered through inhalation. Abstract: The ongoing mutations of the SARS-CoV-2 pose serious challenges to the efficacy …