Direct synthesis of high quantum yield lead-free CsCu2I3 powder in water and its application in yellow LED
For the first time, a simple organic structural unit (2-methylimidazole, 2-MIM) is used to collect a mixture of two metal precursors (CsI and CuI) and
Antigen/adjuvant-free liposome induces adjuvant effects for enhancing cancer immunotherapy
In this study, the authors have developed a library of antigen/adjuvant-free liposomes for testing the adjuvant effects. The anionic liposomes with appropriate surface charges enhance
A pH responsive nanocomposite for combination sonodynamic-immunotherapy with ferroptosis and calcium ion overload via SLC7A11/ACSL4/LPCAT3 pathway
In this research, a nanoparticle formulation, Parthenolide/ICG-CaCO3@Lipid (PTL/ICG-CaCO3@Lip), has been engineered to amplify ferroptosis in tumor cells, positioning it as a potent agent for sonodynamic
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma
An acid-cleavable Tf-modified engineering exosome-based brain-targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co-delivery of siTGF-β and DOX for
Mussel-inspired self-assembly of silver nanoclusters into multifunctional silver aerogels for enhanced catalytic and bactericidal applications
A mussel-inspired self-assembly strategy is proposed to fabricate silver aerogels based on ultrasmall silver nanoclusters through a dopamine-assisted gelation process. The fabricated silver aerogels possess
Bioengineer mesenchymal stem cell for treatment of glioma by IL-12 mediated microenvironment reprogramming and nCD47-SLAMF7 mediated phagocytosis regulation of macrophages
High expression of cellular self-activated immunosuppressive molecules and extensive infiltration of suppressive immune cells in the tumor microenvironment are the main factors leading to the
Short Communication
A novel nanobody broadly neutralizes SARS-CoV-2 via induction of spike trimer dimers conformation
This study describes a novel nanobody that could induce the trimer dimers conformation of the Spike protein to neutralize the SARS-CoV-2 infection. This nanobody exhibits
Nitrogen deficiency modulates carbon allocation to promote nodule nitrogen fixation capacity in soybean
Previously, the effect of soil mineral N deficiency on nodule nitrogen fixation capacity (NFC) is unclear. In this study, we found that N deficiency would
Super-resolution analyzing spatial organization of lysosomes with an organic fluorescent probe
We designed and synthesized an organic small fluorescence probe with a large Stokes shift. With this probe specifically targeting lysosomes, we revealed a distinct spatial
3D-printed microneedles with open groove channels for liquid extraction
This report describes the 3D fabrication of the microneedles with the open groove channels for skin interstitial fluid extraction through capillary force. Biomarkers in the
Multisite PCET with photocharged carbon nitride in dark
Nature relies on the exploitation of sunlight and hydrogen ions to enable uphill organic reactions, namely photosynthesis. Herein, a biomimetic organic semiconductor composed of abundant
Biomimetic assembly to superplastic metal–organic framework aerogels for hydrogen evolution from seawater electrolysis
Superplastic metal–organic framework (MOF) assembled macroscopic architecture is reported for the first time, which can fully and rapidly recover to its initial states…