Perspective

Extracellular matrices (ECMs) play a crucial role in tumor growth and metastases by providing structural support and facilitating tumor cell proliferation. In this review, we explore the development of artificial ECMs engineered through biomineralization, fibrogenesis, and gelation. These bioinspired ECMs create a protective barrier around tumor cells, restricting substance exchange, inhibiting metastases, and potentially inducing …

Biomaterials-Involved Construction of Extracellular Matrices for Tumor Blockade Therapy Read More »

This review discusses design principles, preparation approaches, and performance achievements of metal-organic frameworks (MOF)-based Cu catalysts for electrochemical CO2 reduction to C2+ products. The correlation between synthesis, composition/structure, and catalytic properties was critically discussed to reveal catalytic mechanisms and performance-determining factors. The strategies are suggested to address the remaining challenges for designing advanced MOF-based Cu …

Synthetic Biology-Based Engineering Living Therapeutics for Antimicrobial Application Read More »

This perspective summarizes the approaches for the preparation of lipid nanoparticles (LNPs), the key characterization parameters, in vitro cell experiments, and in vivo animal experiments. The authors hope this perspective can offer valuable guidance to researchers who enter the field of RNA-based LNPs and help them understand the crucial parameters that RNA-based LNPs demand. Abstract: …

A perspective of lipid nanoparticles for RNA delivery Read More »

This perspective explores diverse neural interfaces in the brain, offering transformative possibilities for engaging with our environment and enhancing communication. Emphasis is placed on the role of both non-invasive and invasive neural interfaces in transforming practical applications beyond the realm of healthcare, emphasizing the promising implications for remote control, mind connectivity, and integrated urban design. …

Neural interfaces: Bridging the brain to the world beyond healthcare Read More »

1. “Telemedicine-medical ‘snack community’-PHS ecosystem” indicates the plight during the transformation of traditional culture into sack culture in modern society.2. The supports of regulations made by government and the third-party supervision are prerequisite for medical education and fitness of medical practitioners and patients.3. Constructions of infrastructure, medical education and expertise of medical workers are far …

Telemedicine-medical “snack community”-PHS ecosystem: Insights into the double-edged sword role of telemedicine in clinical practice and medical education during the COVID-19 pandemic and beyond Read More »

The LiF wettable and lithiophilic additive-derived species induce synergistic adsorption with LiF, promoting tiny LiF deposition on the lithium metal anode surface, which provides new insight into the correlation between high LiF content, wettability of LiF, and high-performance LiF-rich solid electrolyte interphase. Abstract: Multi-scale simulation is an important basis for constructing digital batteries to improve …

Insight into uniform filming of LiF-rich interphase via synergistic adsorption for high-performance lithium metal anode Read More »

To realize targeted protein delivery, various stimuli-triggered nanoparticle formulations have been developed. These smart nanoparticles are designed to release cargo proteins, such as antibodies, enzymes, and pro-apoptotic proteins, in response to either internal or external stimuli. This review summarizes recent advances in the design of stimuli-triggered nanomedicine for targeted protein delivery in different biomedical applications. …

Targeted protein delivery based on stimuli-triggered nanomedicine Read More »

This perspective provides a comprehensive overview of the recent research on 3D graphene porous materials (3GPM) with excellent mechanical properties. It analyzes the factors that affect the mechanical behaviour of 3GPM and examines their diverse applications in various fields, such as adsorption, energy storage, solar steam generation, sensors, flexible electronics, and electromagnetic wave shielding. Finally, …

Multifunctional elastomeric composites based on 3D graphene porous materials Read More »

The design strategies of single-atom copper catalysts are briefly summarized and the key factor for their application in industrially electrochemical conversion of CO2 into C2 and C2+ products are pointed out. Abstract: Copper is the only metal that can convert CO2 into C2 and C2+ in electrocatalytic carbon dioxide reduction (CO2RR). However, the Faraday efficiency of CO2 conversion …

Achievements and challenges of copper-based single-atom catalysts for the reduction of carbon dioxide to C2+ products Read More »

Schematic illustration of the therapeutic role and drug development of cannabidiol (CBD) for diabetes. This article comprehensively summarizes the pharmacology and therapeutic role of CBD for diabetes and its complications. Furthermore, the strategies for identifying molecular targets of CBD and developing CBD analogues with greater therapeutic potency have been proposed. Abstract: In recent years, cannabidiol …

The pharmacology and therapeutic role of cannabidiol in diabetes Read More »