Research Article

Matrix-free solid-state RTP with an average lifetime of 0.50 s is realized in the carbon dots (CDs) synthesized by the one-pot hydrothermal process of powder made of feather wastes. The room-temperature phosphorescence lifetime is further prolonged to 1.97 s by employing polyvinyl alcohol (PVA) and phytic acid (PA). Subsequently, a novel CDs/PVA/PA ink is successfully …

High-yield upcycling of feather wastes into solid-state ultra-long phosphorescence carbon dots for advanced anticounterfeiting and information encryption Read More »

An intelligent acid responsive ZIF-8 nanoparticle (CCM + TTD@ZIF-8 NPs) is proposed and is used to promote the healing of burns and infected wounds. It can effectively target bacteria and achieve bacterial imaging under blue light irradiation, effectively releasing CCM and TTD in acidic environments, thereby inhibiting the inflammatory microenvironment and promoting wound healing. Abstract: …

Intelligent bacteria-targeting ZIF-8 composite for fluorescence imaging-guided photodynamic therapy of drug-resistant superbug infections and burn wound healing Read More »

Trilayer scaffolds were fabricated for biomimicking the anatomical structure of the uterine tissue. They could sustainably release estradiol and were able to transform into curved structures to meet the curvature of uterine tissue. They therefore have a high potential for uterine regeneration. Abstract: Scaffold-based tissue engineering provides an efficient approach for repairing uterine tissue defects …

Biomimicking trilayer scaffolds with controlled estradiol release for uterine tissue regeneration Read More »

This study aims to understand ATP synthase inhibitory factor 1’s (ATPIF1’s) role in peripheral nerve regeneration (PNR) using a murine model of sciatic nerve crush injury. Histological exams and behavior assessments revealed ATPIF1 absence hindered nerve tissue reconstruction, delaying sensory and functional recovery. RNA-sequencing showed reduced immune responses in ATPIF1 knockout mice, particularly CCR2/CCL2 signaling-mediated …

Decoding the regulatory role of ATP synthase inhibitory factor 1 (ATPIF1) in Wallerian degeneration and peripheral nerve regeneration Read More »

The current monitoring technologies for biological loads in sewage exhibit drawbacks, including low detection efficiency and insufficient accuracy. The authors’ research team has developed an innovative approach that harnesses the power of the CRISPR/Cas12a system within an automated robot-driven photoelectrochemical biosensing platform. This platform allows early detection and tracking of infectious disease outbreaks, providing timely …

Detection of biological loads in sewage using the automated robot-driven photoelectrochemical biosensing platform Read More »

We explore the rotation of a buckled blister constrained inside an outer ring. The rotation of buckled blister iss actuated via a localized change of curvature, and lower energy-supply is required to initiate the snap-through of buckling compared to conventional bistable mechanism. We experimentally demonstrate the controllability in rotational speed and output torque for a bimetallic …

Motorizing the buckled blister for rotary actuation Read More »

CPC probe with dual response to LDs polarity and mitochondrial ONOO− developed using a toolkit, which indicates an increase in homogeneity of lipid droplets and fibrous-like mitochondria during ferroptosis that inhibits LDs–mitochondrial interactions. Abstract: Super-resolution imaging techniques, such as structured illumination microscopy (SIM), have enabled researchers to obtain nanoscale organelle-level outputs in living systems, but …

Facile construction of dual-response super-resolution probes for tracking organelles dynamics Read More »

Sun et al. report on a personized cancer vaccine generated by irradiating GM-CSF overexpressed tumor cells (providing antigens and stimulation signal for APCs), covalent conjugation with hyaluronic acid (improving the persistence of antigen stimulation). The engineered vaccine activated antitumor immunity responses and prevented tumor growth in mice with a single immunization. Abstract: Vaccine-based therapeutics for …

A self-assembled, genetically engineered, irradiated tumor cell debris vaccine Read More »

The interface of nanocomposite cathode plays a critical role in the performance of proton-conducting solid oxide fuel cells (H-SOFCs), which has been demonstrated by atomic level studies with the first-principles calculations, nanoscale studies by using the pulsed laser deposition method and the prototype fuel cell studies. The resultant BaZr0.4Co0.6O3 cathode leads to a record-breaking power …

Unveiling the importance of the interface in nanocomposite cathodes for proton-conducting solid oxide fuel cells Read More »

To overcome the pharmacological limitations of artemisinin in cancer therapy, the novel pH-responsive artesunate (ARS)-4-hydroxybenzoyl hydrazide (HBZ)-5-amino levulinic acid (ALA) nanoparticles (AHA NPs) with self-supplied capacity of reactive oxygen species (ROS) were reported to realize excellent chemotherapy and chemodynamic therapy (CDT). Abstract: Prodrug-based self-assembled nanoparticles (PSNs) with tailored responses to tumor microenvironments show a significant …

Endoperoxide-enhanced self-assembled ROS producer as intracellular prodrugs for tumor chemotherapy and chemodynamic therapy Read More »